BostonGene Announces Agreement with The University of Texas MD Anderson Cancer Center

Multiple Research Projects Analyze Genomic Data Sets to Understand Disease Progression and Therapeutic Resistance

WALTHAM, MA – September 10, 2019 – BostonGene Corporation (BostonGene), a biomedical software company, today announced an agreement with The University of Texas MD Anderson Cancer Center to work together on multiple research projects to better understand the impact of genome data sets on therapeutic resistance.

Identifying composition and activity of nonmalignant cells within the immune microenvironment of the tumor is becoming critical in determining clinical outcomes, including survival, progression, and therapy response. BostonGene’s solution integrates next-generation sequencing (NGS) obtained from a patient’s tumor with a reference cohort of data from patients with similar diagnosis, simultaneously analyzing tumor and tumor microenvironment activity.

BostonGene delivers oncologist-friendly schematics called MF Portrait™ that depict tumor cellular composition, immune- and stromal microenvironment and activity of tumor-related processes. For one project, BostonGene will assist MD Anderson’s Dr. Michael Wang and his mantle cell lymphoma team by identifying somatic variants, gene expression changes, and tumor microenvironment composition associated with disease progression and other outcomes.

“BostonGene is transforming and personalizing medicine, from treating a diagnosis to treating the person. By partnering with MD Anderson we are closer to understanding why immuno- and targeted therapies are effective for some and not for other patients. Together we are using the BostonGene product to help determine the best treatment for an individual patient,” said Andrew Feinberg, President and CEO of BostonGene.

About BostonGene Corporation
BostonGene Corporation is pioneering the use of biomedical software for advanced patient analysis and personalized therapy decision making in the fight against cancer. BostonGene’s unique solution performs sophisticated analytics to aid clinicians in their evaluation of viable treatment options for each patient’s individual genetics, tumor and tumor microenvironment, clinical characteristics and disease profile. BostonGene’s mission is to enable physicians to provide every patient with the highest probability of survival through optimal cancer treatments using advanced, personalized therapies. For more information, visit BostonGene at http://www.BostonGene.com.

Media Contact:
BostonGene
Erin O’Reilly
+1-781-366-7049
Erin.Oreilly@BostonGene.com

BostonGene Announces Partnership with National Institutes of Health

Precision Medicine Studies Underway to Enable Dynamic Monitoring of Disease Progression and Response to Treatment

WALTHAM, MA – July 23, 2019 – BostonGene Corporation (BostonGene), a biomedical software company, today announced its partnership with the National Institutes of Health (NIH) including the National Cancer Institute (NCI) and the National Institute of Allergy and Infectious Diseases (NIAID).

BostonGene’s solution will provide NCI and NIAID with an interpretation and visualization of a patient’s next-generation sequencing (NGS) information within the landscape of a patient’s genetic and genomic data at a desired level of complexity. The solution will identify all significant somatic alterations, evaluation of protein expression, estimation of tumor heterogeneity, prediction of neoantigens, tumor clonality, hereditary predisposition, viral infestation and pharmacogenomics among other molecular features. BostonGene generates a visually-appealing and self-explanatory tumor schematics, called MF Portrait™, depicting tumor activity, tumor cellular composition, activity of immune-microenvironment and other tumor-associated processes.

“Immuno- and targeted therapies are the most promising and rapidly developing treatments for cancer. BostonGene is thrilled to be partnering with NIH to provide sophisticated data analytics to produce viable treatment options personalized for each patient. Our mission is to treat the patient, not treat the diagnosis,” said Andrew Feinberg, President and CEO of BostonGene.

About BostonGene Corporation
BostonGene Corporation is pioneering the use of biomedical software for advanced patient analysis and personalized therapy decision making in the fight against cancer. BostonGene’s unique solution performs sophisticated analytics to aid clinicians in their evaluation of viable treatment options for each patient’s individual genetics, tumor and tumor microenvironment, clinical characteristics and disease profile. BostonGene’s mission is to enable physicians to provide every patient with the highest probability of survival through optimal cancer treatments using advanced, personalized therapies. For more information, visit BostonGene at http://www.BostonGene.com.

Media Contact:
BostonGene
Erin O’Reilly
+1-781-366-7049
Erin.Oreilly@BostonGene.com

Biomedical Software Startup BostonGene Secures $50M in Series A Financing from NEC

Proceeds to Support Scaling and Advancement of Precision Medicine Computing Platform for Cancer Treatment

Tokyo, April 25, 2019 and Boston, April 24, 2019NEC Corporation (NEC; TSE: 6701) and BostonGene Corporation (BostonGene), a Boston, Mass-based biomedical software company, today announced a US$50M series A strategic investment in BostonGene by NEC.

BostonGene, a pioneer in the use of biomedical software for advanced patient analysis, has discovered, developed, and patented a holistic approach to cancer treatment by defining the optimal therapy combination for individual patients, with a particular focus on immuno- and targeted therapies. BostonGene’s solution includes:

  • Genome and transcriptome sequencing methods to create a patient’s molecular profile.
  • Algorithms that estimate the immune fitness and cancer characteristics of a patient.
  • A continuously updated expert-curated and Artificial Intelligence (AI)-driven database of cancer research and clinical information.
  • Cloud-native software that delivers a patient-prioritized list of best treatment options based on comprehensive data analysis of the tumor and its microenvironment.

Founded in 2015, BostonGene has evaluated its solution utilizing extensive data in close collaboration with many leading cancer centers across the U.S., and has a robust intellectual property portfolio.

The funding will allow BostonGene to accelerate its long-term strategy, enable the expansion of the company’s development efforts, advance its collaboration programs, and support the growth of its talented and diverse team.

“As demonstrated by its remarkable growth and early widespread adoption, BostonGene is leading the precision medicine market in the innovation and development of a mission-critical computing platform,” said Osamu Fujikawa, Senior Vice President and Head of the Business Innovation Unit at NEC Corporation. “NEC and BostonGene share a common vision of the immense potential of an AI-driven approach to cancer immunotherapy. Leveraging the strengths of both companies we will be able to improve the survival rate and quality of life for cancer patients.”

“Transforming and personalizing medicine, from treating a diagnosis to treating the person, is becoming a reality with BostonGene’s unique breakthrough platform. Our early successes validate the market need and the potential of our solution to truly transform cancer treatment and dramatically improve patients’ chances for survival and quality of life. An investment of this magnitude will support our vision, mission and strategy, as well as the formation of synergies with the NEC Health Tech business to create meaningful new opportunities,” said Andrew Feinberg, President and CEO of BostonGene.

About NEC Corporation
NEC Corporation is a leader in the integration of IT and network technologies that benefit businesses and people around the world. The NEC Group globally provides “Solutions for Society” that promote the safety, security, efficiency and equality of society. Under the company’s corporate message of “Orchestrating a brighter world,” NEC aims to help solve a wide range of challenging issues and to create new social value for the changing world of tomorrow. For more information, visit NEC at https://www.nec.com.

About BostonGene Corporation
BostonGene Corporation is pioneering the use of biomedical software for advanced patient analysis and personalized therapy decision making in the fight against cancer. BostonGene’s unique solution performs sophisticated analytics to aid clinicians in their evaluation of viable treatment options for each patient’s individual genetics, tumor and tumor microenvironment, clinical characteristics and disease profile. BostonGene’s mission is to enable physicians to provide every patient with the highest probability of survival through optimal cancer treatments using advanced, personalized therapies. For more information, visit BostonGene at http://www.BostonGene.com.

NEC is a registered trademark of NEC Corporation. All Rights Reserved. Other product or service marks mentioned herein are the trademarks of their respective owners. ©2019 NEC Corporation.

Media Contacts:

BostonGene
Erin O’Reilly
+1-781-366-7049
Erin.Oreilly@BostonGene.com

NEC Corporation
Joseph Jasper
Corporate Communications Division
j-jasper(at)ax.jp.nec.com